[Answer] Which component of the extracellular matrix is responsible for forming proteoglycans?

Answer: Amino sugars
Which component of the extracellular matrix is responsible for forming proteoglycans?

Proteoglycan – Wikipedia

Proteoglycan – Wikipedia

Extracellular matrix – Wikipedia

Proteoglycan – Wikipedia

Proteoglycans are a major component of the animal extracellular matrix the “filler” substance existing between cells in an organism. Here they form large complexes both to other proteoglycans to hyaluronan and to fibrous matrix proteins such as collagen. The combination of proteoglycans and collagen form cartilage a sturdy tissue that is usually heavily hydrated (mostly due to the negatively charged sulfates in the glycosaminoglycan chains of the proteoglycans). They are also involved in binding cations (such as s…

In biology the extracellular matrix (ECM) is a three-dimensional network consisting of extracellular macromolecules and minerals such as collagen enzymes glycoproteins and hydroxyapatite that provide structural and biochemical support to surrounding cells. Because multicellularity evolved independently in different multicellular lineages the composition of ECM varies between multicellular structures; however cell adhesion cell-to-cell communication and differentiation are common functions of the ECM.

Aggrecan also known as cartilage-specific proteoglycan core protein or chondroitin sulfate proteoglycan 1 is a protein that in humans is encoded by the ACAN gene. This gene is a member of the lectican family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Aggrecan is a proteoglycan or a protein modified with large carbohydrates; the human form of the protein …

Fibronectin is a high- molecular weight (~500 kDa) glycoprotein of the extracellular matrix that binds to membrane -spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen fibrin and heparan sulfate proteoglycans (e.g. syndecans).

Laminins are high-mo…

Leave a Reply