[Answer] Tyrosine-kinase receptors are characterized by their _____. (Concept 11.2)

Answer: enzymatic phosphorylation of tyrosine in the receptor protein
Tyrosine-kinase receptors are characterized by their _____. (Concept 11.2)
Receptor tyrosine kinases are the high-affinity cell surface receptors for many polypeptide growth factors cytokines and hormones. Of the 90 unique tyrosine kinase genes identified in the human genome 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. Mutations in receptor tyrosine kinases …
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions as an “on” …
Sat Nov 10 2001 13:30:00 GMT-0500 (Eastern Standard Time) · Receptor tyrosine kinases (RTKs) are transmembrane proteins with an intracellular kinase domain and an extracellular domain that binds ligands; examples include growth factor receptors such as the insulin receptor.
The number of characterized ligands in the TGFβ superfamily far exceeds the number of known receptors suggesting the promiscuity that exists between the ligand and receptor interactions. TGFβ is a growth factor and cytokine involved in paracrine signalling and can be found in many different tissue types including brain heart kidney …
The Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors .The name Wnt is a portmanteau created from the names Wingless and Int-1. Wnt signaling …

Leave a Reply