[Answer] Both _____ and ______ function as introductory drugs that may lead to the use of other psychoactive drugs.

Answer: alcohol and tobacco
Both _____ and ______ function as introductory drugs that may lead to the use of other psychoactive drugs.
A psychoactive drug psychopharmaceutical or psychotropic drug is a chemical substance that changes nervous system function and results in alterations in perception mood consciousness cognition or behavior. These substances may be used medically; recreationally; to purposefully improve performance or alter one’s consciousness; as entheogens for ritual spiritual or shamanic purp…
A psychoactive drug psychopharmaceutical or psychotropic drug is a chemical substance that changes nervous system function and results in alterations in perception mood consciousness cognition or behavior. These substances may be used medically; recreationally; to purposefully improve performance or alter one’s consciousness; as entheogens for ritual spiritual or shamanic purposes; or for research. Some categories of psychoactive drugs which have therapeutic value are prescribed by physicians and other healthcare practitioners. Examples include anesthetics analgesics anticonvulsant and antiparkinsonian drugs as well as medications used to treat neuropsychiatric disorders such as antidepressants anxiolytics antipsychotics and stimulant medications. Some psychoactive substances may be used in the detoxification and rehabilitation programs for persons dependent on or addicted to other psychoactive drugs . Psychoactive substances often bring about subjective (although these may be objectively observed) changes in consciousness and mood that the user may find rewarding and pleasant (e.g. euphoria or a sense of relaxation) or advantageous in an objectively observable or measurable way (e.g. increased alertness). Substances which are rewarding and thus positively reinforcing have the potential to induce a state of addiction – compulsive drug use despite negative consequences. In addition sustained use of some substances may produce physical or psychological dependence or both associated with somatic or psychological-emotional withdrawal states respectively. Drug rehabilitation attempts to reduce addiction through a combination of psychotherapy support groups and other psychoactive substances. Conversely certain psychoactive drugs may be so unpleasant that the person will never use the substance again. This is especially true of certain deliriants (e.g. Jimson weed) powerful dissociatives (e.g. Salvia divinorum) and classic psychedelics (e.g. LSD … Read more on Wikipedia
Psychoactive drug use can be traced to prehistory . There is archaeological evidence of the use of psychoactive substances (mostly plants) dating back at least 10 000 years and historical evidence of cultural use over the past 5 000 years. The chewing of coca leaves for example dates back over 8 000 years ago in Peruvian society.
Psychoactive drug use can be traced to prehistory . There is archaeological evidence of the use of psychoactive substances (mostly plants) dating back at least 10 000 years and historical evidence of cultural use over the past 5 000 years. The chewing of coca leaves for example dates back over 8 000 years ago in Peruvian society. Medicinal use is one important facet of psychoactive drug usage. However some have postulated that the urge to alter one’s consciousness is as primary as the drive to satiate thirst hunger or sexual desire. Supporters of this belief contend that the history of drug use and even children’s desire for spinning swinging or sliding indicate that the drive to alter one’s state of mind is universal. One of the first people to articulate this point of view set aside from a medicinal context was American author Fitz Hugh Ludlow (1836–1870) in his book The Hasheesh Eater (1857): [D]rugs are able to bring humans into the neighborhood of divine experience and can thus carry us up from our personal fate and the everyday circumstances of our life into a higher form of reality. It is however …

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